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Methods in Enzymology, Volume 403: GTPases Regulating Membrane Targeting and Fusion

Unknown Author
4.9/5 (20283 ratings)
Description:Rab GTPases now comprise a family of >63 members. They are emerging as the key hub element controlling the membrane architecture of eukaryotic cells. They are intimately involved in vesicle targeting and fusion in both the endocytic and exocytic pathways and direct the assembly and disassembly of protein complexes that include regulators (GEFs and GAPs), effectors (tethers/motors) and fusion components (SNAREs) that control membrane targeting and fusion. During the last 3 years the field has virtually exploded with the identification and characterization of many new Rab proteins and their effectors. Our understanding of how Rab GTPases control membrane function remains at its infancy. This volume of MIE provides a wealth of new concepts, approaches and tools to study Rab proteins in the test tube and in living cells that will be of strong benefit to both established laboratories and new investigators in the field to elucidate Rab GTPase function in cellular development, differentiation and proliferation. * Comprehensive overview of Rab GTPase phylogeny and systems biology* Identification and characterization of Rab GEFs, GAPs and effectors* General methodologies to study Rab GTPase function in vitro and in vivo using biochemical, molecular and microscopy approachesWe have made it easy for you to find a PDF Ebooks without any digging. And by having access to our ebooks online or by storing it on your computer, you have convenient answers with Methods in Enzymology, Volume 403: GTPases Regulating Membrane Targeting and Fusion. To get started finding Methods in Enzymology, Volume 403: GTPases Regulating Membrane Targeting and Fusion, you are right to find our website which has a comprehensive collection of manuals listed.
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Pages
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PDF, EPUB & Kindle Edition
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Release
ISBN
0121828085

Methods in Enzymology, Volume 403: GTPases Regulating Membrane Targeting and Fusion

Unknown Author
4.4/5 (1290744 ratings)
Description: Rab GTPases now comprise a family of >63 members. They are emerging as the key hub element controlling the membrane architecture of eukaryotic cells. They are intimately involved in vesicle targeting and fusion in both the endocytic and exocytic pathways and direct the assembly and disassembly of protein complexes that include regulators (GEFs and GAPs), effectors (tethers/motors) and fusion components (SNAREs) that control membrane targeting and fusion. During the last 3 years the field has virtually exploded with the identification and characterization of many new Rab proteins and their effectors. Our understanding of how Rab GTPases control membrane function remains at its infancy. This volume of MIE provides a wealth of new concepts, approaches and tools to study Rab proteins in the test tube and in living cells that will be of strong benefit to both established laboratories and new investigators in the field to elucidate Rab GTPase function in cellular development, differentiation and proliferation. * Comprehensive overview of Rab GTPase phylogeny and systems biology* Identification and characterization of Rab GEFs, GAPs and effectors* General methodologies to study Rab GTPase function in vitro and in vivo using biochemical, molecular and microscopy approachesWe have made it easy for you to find a PDF Ebooks without any digging. And by having access to our ebooks online or by storing it on your computer, you have convenient answers with Methods in Enzymology, Volume 403: GTPases Regulating Membrane Targeting and Fusion. To get started finding Methods in Enzymology, Volume 403: GTPases Regulating Membrane Targeting and Fusion, you are right to find our website which has a comprehensive collection of manuals listed.
Our library is the biggest of these that have literally hundreds of thousands of different products represented.
Pages
Format
PDF, EPUB & Kindle Edition
Publisher
Release
ISBN
0121828085
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