Read Methods in Enzymology, Volume 451: Autophagy: Lower eukaryotes and non-mammalian systems, Part A

Methods in Enzymology, Volume 451: Autophagy: Lower eukaryotes and non-mammalian systems, Part A

Daniel Klionsky

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Description:This is the companion volume to Daniel Klionsky's "Autophagy: Lower Eukaryotes," which features the basic methods in autophagy covering yeasts and alternative fungi (aspergillus, podospora, magnaporthe). Klionsky is one of the leading authorities in the field. He is the editor-in-chief of "Autophagy." The November 2007 issue of "Nature Reviews" highlighted his article, "Autophagy: from phenomenology to molecular understanding in less than a decade.? He is currently editing guidelines for the field, with 230 contributing authors, that will publish in "Autophagy." Particularly in times of stress, like starvation and disease, higher organisms have an internal mechanism in their cells for chewing up and recycling parts of themselves. The process of internal "house-cleaning? in the cell is called autophagy - literally self-eating. Breakthroughs in understanding the molecular basis of autophagy came after the cloning of ATG1 (autophagy-related gene 1) in yeast. (To date, 30 additional yeast genes have been identified.) These ATG genes in yeast were the stepping stones to the explosion of research into the molecular analysis of autophagy in higher eukaryotes. In the future, this research will help to design clinical approaches that can turn on autophagy and halt tumor growth. *Establishes the functional roles of specific cellular proteins in selective and nonselective autophagy in mammalian cells which aids researchers in determining why autophagy is shut down in neoplastia (growth of abnormal tissue mass) and turned on during bacterial invasion. *Includes methods to evaluate the role of autophagy in the drug-induced cell death of cancer cells in culture, which helps researchers design clinical approaches that can turn on autophagy and halt tumor growth. *Covers higher eukaryotes including lifespan in C. elegans to marine organisims and bridging into the clinical aspects, including autophagy in chronic myelogenous leukemia (CML is one of four types of leukaemia), lung cancer, prostate cancer, and cardiac cells.We have made it easy for you to find a PDF Ebooks without any digging. And by having access to our ebooks online or by storing it on your computer, you have convenient answers with Methods in Enzymology, Volume 451: Autophagy: Lower eukaryotes and non-mammalian systems, Part A. To get started finding Methods in Enzymology, Volume 451: Autophagy: Lower eukaryotes and non-mammalian systems, Part A, you are right to find our website which has a comprehensive collection of manuals listed.
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Pages: 500

Format: PDF, EPUB & Kindle Edition

Publisher: Academic Press

Release: 2011

ISBN: 1282286706

Description: This is the companion volume to Daniel Klionsky's "Autophagy: Lower Eukaryotes," which features the basic methods in autophagy covering yeasts and alternative fungi (aspergillus, podospora, magnaporthe). Klionsky is one of the leading authorities in the field. He is the editor-in-chief of "Autophagy." The November 2007 issue of "Nature Reviews" highlighted his article, "Autophagy: from phenomenology to molecular understanding in less than a decade.? He is currently editing guidelines for the field, with 230 contributing authors, that will publish in "Autophagy." Particularly in times of stress, like starvation and disease, higher organisms have an internal mechanism in their cells for chewing up and recycling parts of themselves. The process of internal "house-cleaning? in the cell is called autophagy - literally self-eating. Breakthroughs in understanding the molecular basis of autophagy came after the cloning of ATG1 (autophagy-related gene 1) in yeast. (To date, 30 additional yeast genes have been identified.) These ATG genes in yeast were the stepping stones to the explosion of research into the molecular analysis of autophagy in higher eukaryotes. In the future, this research will help to design clinical approaches that can turn on autophagy and halt tumor growth. *Establishes the functional roles of specific cellular proteins in selective and nonselective autophagy in mammalian cells which aids researchers in determining why autophagy is shut down in neoplastia (growth of abnormal tissue mass) and turned on during bacterial invasion. *Includes methods to evaluate the role of autophagy in the drug-induced cell death of cancer cells in culture, which helps researchers design clinical approaches that can turn on autophagy and halt tumor growth. *Covers higher eukaryotes including lifespan in C. elegans to marine organisims and bridging into the clinical aspects, including autophagy in chronic myelogenous leukemia (CML is one of four types of leukaemia), lung cancer, prostate cancer, and cardiac cells.We have made it easy for you to find a PDF Ebooks without any digging. And by having access to our ebooks online or by storing it on your computer, you have convenient answers with Methods in Enzymology, Volume 451: Autophagy: Lower eukaryotes and non-mammalian systems, Part A. To get started finding Methods in Enzymology, Volume 451: Autophagy: Lower eukaryotes and non-mammalian systems, Part A, you are right to find our website which has a comprehensive collection of manuals listed.
Our library is the biggest of these that have literally hundreds of thousands of different products represented.

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Methods in Enzymology, Volume 451: Autophagy: Lower eukaryotes and non-mammalian systems, Part A

Methods in Enzymology, Volume 451: Autophagy: Lower eukaryotes and non-mammalian systems, Part A

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